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Introduction: Recurrent respiratory infections (RRI) represent a widespread condition in childhood. Now we have limited data about the course of the SARS-CoV-2 infection among children with RRI. Objective(s): The aim of our study was to describe clinical features of COVID-19 among children with RRI in comparison to occasionally ill children in Ukraine. Material(s) and Method(s): Study of 150 pediatric patients from different regions of Ukraine, aged from 4 to 18. Group 1-79 (52,6%) children with RRI more than eight episodes per year, group 2 - occasionally ill children 71 (47,4%),after laboratory-confirmed Covid-19 three months ago, in a period from March to May 2021. Result(s): The most common symptoms of 150 pediatric patients were fever (78,5%), dry cough (53%), rhinitis (50%), fatigue (25,0%), diarrhea (16,6%). We observed no statistical differences in clinical manifestations of COVID-19 among groups of children. However, in children with RRI the rate of hospitalization was longer (44,3%) versus (15,4%) and the duration of a hospital stay was longer-14,3+/-1,5;versus children occasionally ill children-6+/-0,9 (p<0,001). Children with RRI had more fever days 4,7+/-0,7, versus 3,2+/-0,7 and had a prolonged catarrhal period-7,3+/-0,7 versus 5,1+/-0,8 (p<0,001). No statistically significant differences were found between the study groups on any laboratory parameters. Conclusion(s): The course of SARS-CoV-2 infection among children with RRI was more severe: a higher rate of hospitalization was detected, severe intoxication syndrome, longer duration of a hospital stay and catarrhal period. This research will give additional information about the course of SARS-CoV-2 infection among children with RRI.
ABSTRACT
In modern business conditions, an important factor in financial and economic activities is employees, their competence, and professionalism. Globalization processes in the economic environment motivate the use of new information resources and technologies, the development of the economy's new areas. At the same time, there is a growing need for a high level of human capital development. Therefore, today it is necessary to develop and implement measures aimed at investing in human capital. In the context of the COVID-19 pandemic, investing in human capital is more vital than ever, as it can lay the foundation for sustainable, comprehensive recovery and growth in the future. It is investments in technology, education, science that guarantee the formation of highly qualified competitive human capital at all levels of the economy. Hence, one of the main tasks of the company is to support and constantly improve the skills of its employees, the formation of such skills and abilities that would allow them to quickly adapt to innovative technologies and complex realities of the modern economy. The purpose of the article is to review the foreign experience of developed countries in solving social problems that affect the human capital index. Studying the world experience of human capital formation and borrowing it for Ukraine can be an effective tool of state social policy. After all, investments in physical capital and infrastructure without sufficient investments in human capital may not give Ukraine the expected dividends. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
ABSTRACT
In modern business conditions, an important factor in financial and economic activities is employees, their competence, and professionalism. Globalization processes in the economic environment motivate the use of new information resources and technologies, the development of the economy’s new areas. At the same time, there is a growing need for a high level of human capital development. Therefore, today it is necessary to develop and implement measures aimed at investing in human capital. In the context of the COVID-19 pandemic, investing in human capital is more vital than ever, as it can lay the foundation for sustainable, comprehensive recovery and growth in the future. It is investments in technology, education, science that guarantee the formation of highly qualified competitive human capital at all levels of the economy. Hence, one of the main tasks of the company is to support and constantly improve the skills of its employees, the formation of such skills and abilities that would allow them to quickly adapt to innovative technologies and complex realities of the modern economy. The purpose of the article is to review the foreign experience of developed countries in solving social problems that affect the human capital index. Studying the world experience of human capital formation and borrowing it for Ukraine can be an effective tool of state social policy. After all, investments in physical capital and infrastructure without sufficient investments in human capital may not give Ukraine the expected dividends. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
ABSTRACT
BackgroundAcute respiratory viral infections (ARVI) continue to be the main reason for seeking pediatric care in Ukraine. Comparative characteristics of etiological spectrum of ARVI in Ukrainehas not been sufficiently studied.Aim of Study to investigate the etiology of ARVIand compare it between epidemiological seasons 2018-2019 and 2019-2020.MethodsThe study was conducted inthe Eurolab clinic (Kyiv, Ukraine) during the period 2018-2020. Nasopharyngeal swabs, collected from ARVI children aged 2 months to 16 years old, were analyzed by multiplex real time polymerase chain reactionfor 7 viruses – Respiratory Syncytial virus (RSV), Parainfluenza virus (PIV), Adenovirus (AdV), human Metapneumovirus (hMPV), Rhinovirus (RV), human Bocavirus (hBoV) and Coronavirus (CoV). Rapid influenza diagnostic testing was used.Results147 samples were collected during the period from October 2018 until February 2019;125 (85,0%) were positive: hMPV – 33 (26,3%), IVA – 28 (22,4%), RV – 21 (16,8%), RSV – 10 (8,0%), hBoV – 7 (5,6%), AdV – 5 (4,0%), PIV – 4 (3,4%). Diagnosis of pneumonia was established in 18% of children infected by hMPV and 21% of children with IVA infection. Other clinical manifestations of hMPV infection were: tracheobronchitis, obstructive bronchitis, bronchiolitis, rhinopharyngitis, laryngitis.12 of the children with RV infection had symptoms of rhinopharyngitis, wheezing, bronchitis and laryngitis. 203 nasopharyngeal swabs were collected during epidemic season 2019-2020, 180 (88,7%) of them were positive: RV – 56 (31,7%), AdV – 39 (22,2%), CoVNL-63, 229E – 28 (12,7%), hBoV – 19 (10,6%), IVA -15 (8,3%), PIV – 12 (6,6%). Confirmed diagnosis of pneumonia had 6 (10,6%) children with RV. 10 (17,8%) children with AdV infection had pneumonia as a clinical manifestation. CoVNL-63, 229E caused rhinopharyngitis, croup, wheezing, tracheobronchitis. Generally, 103 samples were collected during the period from March 2019 until September 2019. 98 of them were positive: RSV -37 (37,8%), RV -29 (29,6%),CoV – 12 (12,2%), AdV – 10 (10,2%), PIV – 9 (9,2%).ConclusionsThere has been a change in the etiological spectrum of ARVI during the last two years. During epidemic season 2018-2019 in Ukraine, the most prevalent viruses were hMPV -33 (26,3%), IVA -28 (22,4%), RV – 21 (16,8%). During epidemic season 2019-2020 the most commonlydetected pathogens were RV- 56 (31,7%), AdV 39 (22,2%), CoVNL -63, 229E28 (12,7%).Epidemiological studies should be continued in order to forecast the probable clinical course of disease, and for optimization therapy.
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OBJECTIVE: The aim: Is to provide data on the presence of potential pathogens of ARTIs in children in Ukraine. PATIENTS AND METHODS: Materials and methods: The etiology of ARTIs was investigated in 487 children in MC 'Eurolab', Kyiv, Ukraine during 2018-2020 years. Seven respiratory viruses - Respiratory Syncytial virus (RSV), Parainfluenza virus (PIV), Adenovirus (AdV), human Metapneumovirus (MPV), Rhinovirus (RV), human Bocavirus (BoV), Coronavirus (CoV), were identified by PCR. Qualitative detection of Influenza type A, type B, Group A Streptococcal was performed by chromatographic immunoassay. Pathogens profiles, clinical characteristics and seasonality were analyzed. RESULTS: Results: 487 nasal and throat swabs from children with ARVI were collected. 400 (82,1%) samples were found to be positive: 319 swabs were positive at least for one respiratory virus, 43 children had positive rapid influenza test, 38 - positive strep test. A total of 403 viruses were identified. RV (27,1%), ADV (13,4%), RSV (13,2 %), IVA (10,7 %) were the most commonly identified viruses. CONCLUSION: Conclusions: Detection of viral seasonality in Ukraine and estimating of clinical features in case of infection allows predicting probable clinical course of disease, to provide, optimize the therapy and to develop preventive measures, vaccination, in particular.
ABSTRACT
The urgency and urgent necessity to develop a research topic are due to a number of factors. First of all, the legal community unanimously reached a consensus on the necessity to reform the institution of notaries in the direction of expanding the powers and functions of public and private notaries, increasing the requirements for these participants in the context of the procedure of certification of transactions (contracts) in various fields. The reform of the Ukrainian notary has recently exhausted its potential and positive expectations on the part of civil society, which is only complicated by the progressive situation with the spread of acute respiratory infections caused by the COVID-19 SARSCoV-2 virus. The purpose of this article was to objectively outline the existing problems in the field of law enforcement, related to the peculiarities of electronic transactions that require notarization, with the formulation of author's proposals to improve legislation in this area. The study was conducted using a number of general and special methods, a key role among which was played by comparative legal and statistical-prognostic methods, which were used to thoroughly analyze the current state of affairs in the field of electronic certification of transactions by notaries. As a result of the study, the authors concluded that in the development of the global information society and digital economy, the issue of electronic transactions requiring notarization needs further involvement of both theoretical and scientific research, as well as the development of practical solutions and proposals to improve the electronic interaction system. © 2021 Lifescience Global